Influence from genetic variants regarding MATE1 into transport and you will protein localization
Inspection of your own NCBI SNP databases found the current presence of around three missense mutations found in the coding series out-of SLC47A1. 404T>C (rs35646404) which have a not known frequency results in a keen amino acid exchange inside status 159 (p.159T>M). At exactly the same time, the newest coding polymorphisms c.1012G>An excellent (p.338V>I, rs35790011) and you may c.1490G>T (p.497C>F; rs35395280) on the pursuing the heterozygosity frequencies off 0.065 and 0.023, correspondingly, was indeed typed on databases. (more…)
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Influence from genetic variants regarding MATE1 into transport and you will protein localization